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Scientific Articles

Our founders, Dr. Federico Nicolosi and Dr. Giannantonio Spena, present their scientific paper on 3D VIR (Virtual Intraoperative Reconstruction), a method of digital reconstruction which converts intraoperative scenarios in 3d textured models. The study provides the application of a reconstruction method which represents a key point in the development of neurosurgical education. In 2015, this astonishing result inspired the UpSurgeOn foundation.

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The American College of Surgeons suggests a few recommendations regarding the protection of workers during COVID-19 pandemic, thanks to the experience collected and reported by other centers. The article underlines which strategies should be adopted to operate safely and to protect your family when returning home. Additional online resources are available in the text to provide comprehensive technical insights.

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Monday, 30 March 2020 11:29

UCLA 100 Subjects in Neurosurgery

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The 100 UCLA Subjects in Neurosurgery is an educational resource of neurological topics created by the UCLA Department of Neurosurgery. Experts of different subspecialties offer a comprehensive description of diseases, treatment choices, and surgical procedures, to be accessible for all residents of any levels. The collection represents unmissable support for any neurosurgeon interested in consolidating its theoretic skills. Stay at home and continue to improve your education.

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What should we do when a Covid-19 patient (or a suspect) needs a surgical treatment? In this article, the authors provide guidelines for the management of COVID-19 cases, focusing on the characteristics and preparation of the operating room, personal protective equipment for all the staff, and the guidance for moving the patient.

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Sodium fluorescein (SF) is a water-soluble fluorophore emitting a green-yellow glow when hit by ultraviolet rays. It has been used in the field of ophthalmology for decades, and now, due to its ability to spread in areas with blood-brain barrier damage, it is increasingly applied also in neurosurgery. In this study, the purpose of the authors is to offer a critical analysis of the use of SF for surgical resection of central nervous tumors in the pediatric population.

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Myelopathy represents a challenge in neurology and neurosurgery. Nowadays, its pathophysiology and evolution are still not completely understood. Prompt interventions and correct treatment options constitute the main determinants of short and long term prognosis. Which elements could help the clinicians to predict the prognosis? In this study, conducted by the World Federation of Neurosurgical Societies (WFNS) spine committee, the authors performed a comprehensive review of recent literature. The aim was to describe outcome measures, clinical and radiological variables that could influence the prognosis in patients with cervical spondylotic myelopathy.

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The cervical spondylotic myelopathy (CSM) is a progressive disease often caused by trauma, tumors, inflammatory, and degenerative processes (intervertebral disc herniation or spondylosis). The signs and symptoms develop because of spinal cord injury or interruption of the physiological transmission of nerve impulses.
 
The goal of treatment is to relieve pressure on the spinal cord and to prevent the progression of symptoms. However, clinical improvement may not occur.
 
This study, conducted by the World Federation of Neurosurgical Societies (WFNS) Spine Committee, is an exhaustive literature review of the available English articles published during the last ten years. 
The aim is to offer recommendations and surgical indications on the management of CSM sharing knowledge and practical skills in the field of spinal surgery. 
 

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The introduction of 3D digital technologies in medicine has represented a radical change, in particular in neurosurgery education. Thanks to the realization of 3D atlases and brain models, digital applications and combination of VR (virtual reality) with 3D printed physical models, the study of neuroanatomy is completely revolutionized. Moreover, these technologies allow the planning and simulation of surgical techniques, enhancing manual and mental skills.

In this article, the authors offer a comprehensive description of the current hi-tech contents in the era of modern neurosurgical education. 

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In the last years the introduction of genomics has represented a turning point, expanding the knowledge in the field of tumoral biology and determining changes in their management. The application of those discoveries have been extensively studied and applied in cranial pathologies, but not in the spinal counterpart. Could these additional information change the treatment strategies of spinal tumors in order to improve clinical outcome?

In this article the authors report an exhaustive description about standard of care, molecular characterization and targeted therapies of the principal primary spinal tumors (intramedullary spinal cord tumors, intradural extramedullary tumors and primary spinal column malignancies).

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DVAs (Developmental Venous Anomalies) are malformations of parenchyma drainage affecting cerebral veins. Also called venous angiomas, these lesions are usually supratentorial and composed of dilated medullary veins (caput medusae sign) arranged in a radial manner.

In this article the authors analyze DVAs characterized by shunts themselves (transitional venous anomalies) or related to cerebral arteriovenous malformations (AVMs). The aim of the study is to underline the differences of these two subgroups considering the clinical features, the treatment strategies used in the management and the outcome.

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